European XFEL
Single Particles, Clusters, and Biomolecules & Serial Femtosecond Crystallography (SPB/SFX)

 

The Single Particles, Clusters, and Biomolecules & Serial Femtosecond Crystallography (SPB/SFX) instrument of the European XFEL is primarily concerned with three-dimensional diffractive imaging, and three-dimensional structure determination, of micrometre-scale and smaller objects, at atomic or near-atomic resolution.

A particular emphasis is placed on biological objects—including crystals of macromolecules and macromolecular complexes as well as viruses, organelles, and cells—though the instrument will also be capable of investigating non-biological samples using similar techniques. Furthermore, the SPB/SFX instrument aims to study structural dynamics in these biological systems on the millisecond to femtosecond timescale.

The SPB/SFX instrument consists of two experiment endstations (upstream and downstream), based on the combined contributions of European XFEL and the Serial Femtosecond Crystallography (SFX) user consortium.

 

 

 

Detectors

AGIPD - 1 Mpx

Type
The upstream 1 Mpx detector can be placed between distances of 0.13 m and ~6 m distance to the upstream interaction region
Time Resolved
Yes
Pixel Size
X = 200 [um], Y = 200 [um]
Passive or Active (Electronics)
Active
Dynamic Range
1 * 104 [photons/px]

Detection

Detected Particle
Photon

AGIPD - 4 Mpx

Description
The downstream 4 Mpx detector features sample-detector distances between 0.12 m and 0.52 m
Time Resolved
Yes
Pixel Size
X = 200 [um], Y = 200 [um]
Passive or Active (Electronics)
Active
Dynamic Range
1 * 104 [photons/px]

Detection

Detected Particle
Electron
contacts
Adrian Mancuso
Techniques
Diffraction
  • Crystallography
  • Crystallography (biological macromolecules)
  • Time-resolved studies
Imaging
  • Coherent diffractive imaging
  • Ptychography
  • X-ray holography
Scattering
  • Anomalous scattering
  • Coherent scattering
  • Elastic scattering
  • Resonant scattering
  • Small angle scattering
  • Time-resolved scattering
  • Wide angle scattering
Disciplines
Life Sciences & Biotech
  • Biophysics
  • Protein and macromolecular structures
  • Technique Development - Life Sciences & Biotech
Material Sciences
  • Technique Development - Material Sciences
Physics
  • Atomic & molecular physics
  • Optics
  • Soft condensed matter physics
  • Technique Development - Physics
control/Data analysis
Control Software Type
  • n/a
Data Output Type
  • n/a
Data Output Format
  • n/a
Softwares For Data Analysis
  • Major user-developed code for SFX available for users. Please contact us.
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