European Synchrotron Radiation Facility
ID17 - Biomedical Beamline

ID17 is dedicated to biomedical imaging, radiation biology and radiation therapy; experiments can be performed in-vitro or in-vivo in two endstations which work alternatively.

The first endstation, located at ~40 meters from the source, can use filtered white beam with a very high flux. The maximum beam size at this point is 35x2 mm2 (hxv).

The second endstation, located at ~150 meters from the source, can only use monochromatic beam, from 25 keV to 150 keV, with a maximum beam size of 150x6 mm2 (hxv).

 

 

 

Beamline Energy Resolution
1 * 1010 [meV] @ 33 [eV]
1 * 1010 [meV] @ 33 [eV]
Beamline Energy Range
25000 - 160000 [eV]
Max Flux On Sample
2 * 1014 [ph/s] @ 33 [eV]
Spot Size On Sample Hor
100 - 150000 [um]
Spot Size On Sample Vert
100 - 6000 [um]
Divergence Hor
0 - 1 [mrad]
Photon Sources

W125 wiggler

Type
Wiggler
Available Polarization
Linear horizontal
Source Size Sigma
X = 94 [um], Y = 2.3 [um]
Deflection Parameter K
17.5
Energy Range
1 - 600 [keV]
Number Of Periods
12
Period
125 [mm]

W150 wiggler

Type
Wiggler
Available Polarization
Linear horizontal
Source Size Sigma
X = 94 [um], Y = 2.4 [um]
Deflection Parameter K
22.3
Energy Range
1 - 600 [keV]
Number Of Periods
11
Period
150 [mm]
Monochromators

Bragg-Bragg

Energy Range
40 - 120 [eV]
Type
Double crystal Si(111); Bragg-Bragg geometry (fixed-exit)
Resolving Power
1 * 10-4 [deltaE/E] @ 50000 [eV]
Pre-focusing Mirror Type
None
Refocusing Mirror Type
None

Laue-Laue

Energy Range
27000 - 150000 [eV]
Type
Double Si(111) crystals; Laue-Laue geometry
Resolving Power
1 * 10-3 [deltaE/E] @ 30000 [eV]
Pre-focusing Mirror Type
None
Refocusing Mirror Type
None

Multilayer

Energy Range
20000 - 60000 [eV]
Type
Double C/W mirrors; 20 Å d-spacing; Bragg-Bragg geometry
Resolving Power
1 * 10-2 [deltaE/E]
Pre-focusing Mirror Type
None
Refocusing Mirror Type
None

Single Laue monochromator

Energy Range
30000 - 80000 [eV]
Type
Single Si(111) crystal; 2.5 mm thick; asymmetry angle: 1.2 degrees; Laue geometry
Pre-focusing Mirror Type
None
Refocusing Mirror Type
None
Other Optics

Beam filters

Description
Set of in-vacuum (C, Al, Cu, Au) and in-air (PMMA) filters
Endstations or Setup

Monochromatic beam station

Microscopes
None
Diffractometer
- Large sample computed tomography station
- High resolution computed tomography station
- Large sample platform for general purposes
Spectrometer
None
Detectors Available
8 micron pixel detector (monochromatic)
47 micron pixel detector (monochromatic beam)
3.0-6.0 micron pixel detector (monochromatic)
23 micron pixel detector (monochromatic beam)
2-line Germanium detector
Endstation Operative
Yes

Pink beam station

Microscopes
None
Diffractometer
- Kappa-type diffractometer (Huber) used for sample positioning. Used for sample irradiation in pink beam radiotherapy
- Optional high resolution computed tomography station
Spectrometer
None
Detectors Available
0.7-1.4 micron microscope (pink beam)
23 micron pixel detector (pink beam)
Endstation Operative
Yes

Sample

Sample Type
Other: For radiation biology and radiation therapy: cells, in-vivo samples (<30 kg), dosimeters. For high resolution imaging: any type of samples
Mounting Type
For imaging: The sample sizes are the maximum allowed
Required Sample Size
X = 40 [mm], Y = 40 [mm], Z = 80 [mm]
Detectors

0.7-1.4 micron microscope (pink beam)

Type
PCO Edge mounted on a Optics Peter microscope
Description
0.7/1.4 micron pixel microscopes for high resolution computed tomography imaging; coupled to a PCO.Edge.5.5 camera;
scintillators: GGG:Eu; LuAG:Ce
Pixel Size
X = 1 [um], Y = 1 [um]
Array Size
X = 2560 [pixel], Y = 2180 [pixel]
Passive or Active (Electronics)
Active

Detection

Detected Particle
Photon

23 micron pixel detector (monochromatic beam)

Type
PCO Edge 5.5 camera mounted on an optics
Description
PCO Edge 5.5 camera mounted on a home assembled optics. Scintillator: gadox, LuAG:Ce, YAG:Ce
Pixel Size
X = 23 [um], Y = 23 [um]
Array Size
X = 2560 [pixel], Y = 2180 [pixel]
Passive or Active (Electronics)
Active

Detection

Detected Particle
Photon

23 micron pixel detector (pink beam)

Type
Frelon camera mounted on an optics; adapted for pink beam imaging
Description
Frelon 2kx2k camera mounted on a home assembled optics. Scintillator: gadox
Pixel Size
X = 23 [um], Y = 23 [um]
Array Size
X = 2048 [pixel], Y = 2048 [pixel]
Passive or Active (Electronics)
Active

Detection

Detected Particle
Photon

2-line Germanium detector

Type
High purity Germanium detector.
Description
Two lines of 432 pixels; direct conversion;
Pixel Size
X = 350 [um], Y = 10000 [um]
Array Size
X = 432 [pixel], Y = 2 [pixel]
Thickness
1 [mm]
Passive or Active (Electronics)
Active

Detection

Detected Particle
Photon

3.0-6.0 micron pixel detector (monochromatic)

Type
PCO Edge 5.5 camera mounted on an optics
Description
PCO Edge 5.5 camera mounted on a home made optics. Pixel size can be swapped between 3.0 and 6.0 microns.
Scintillators: LuAG:Ce; YAG:Ce
Pixel Size
X = 3 [um], Y = 3 [um]
Array Size
X = 2560 [pixel], Y = 2180 [pixel]
Passive or Active (Electronics)
Active

Detection

Detected Particle
Photon

47 micron pixel detector (monochromatic beam)

Type
Frelon camera mounted on an optics
Description
Frelon 2kx2k camera mounted on a home assembled optics. Scintillator: gadox, LuAG:Ce, YAG:Ce
Pixel Size
X = 47 [um], Y = 47 [um]
Array Size
X = 2048 [pixel], Y = 2048 [pixel]
Thickness
60 [um]
Passive or Active (Electronics)
Active

Detection

Detected Particle
Photon

8 micron pixel detector (monochromatic)

Type
Frelon camera mounted on an optics
Description
Frelon 2kx2k camera mounted on a home made optics. Scintillator: gadox screen
Pixel Size
X = 8 [um], Y = 8 [um]
Array Size
X = 2048 [pixel], Y = 2048 [pixel]
Thickness
10 [um]
Passive or Active (Electronics)
Active
Dynamic Range
16 [bits]

Detection

Detected Particle
Photon
Support Laboratories

Beamline laboratories

Description

Small mechanical workshop; at the monochromatic beam station

Sample preparation hood adapted to specific nanoparticle preparations; at the pink beam station

Biomedical facility

Description

The BMF includes 5 laboratories: the animal facility, the L1 cell confinement, the L2 cell confinement, the sample preparation lab and the histology laboratory.

The BMF provides service to ESRF users requiring cell and/or animal experimentation in correspondence with their allocated beamtime as well as in-house research.


contacts
Herwig REQUARDT
Elke BRAUER-KRISCH
Alberto BRAVIN
Alexander RACK
Techniques
Imaging
  • Medical application
  • X-ray microscopy
  • X-ray tomography
Disciplines
Humanities
  • Other - Humanities
Life Sciences & Biotech
  • Food quality and safety
  • Medicine
  • Other - Life Sciences & Biotech
  • Veterinary sciences
Material Sciences
  • Knowledge based multifunctional materials
Address
ESRF, 71 Avenue des Martyrs, 38043 Grenoble, France
control/Data analysis
Control Software Type
  • Spec
Data Output Type
  • 2D and 3D images
Data Output Format
  • RAW, TIFF or ESRF-binary type (.edf)
Softwares For Data Analysis
  • ImageJ, Matlab, PyMCA, Inhouse
Equipment That Can Be Brought By The User
Please contact beamline staff: the experimental hutches fit a wide range of setups