I04-1 is a fixed wavelength monochromatic beamline, with its undulator in I04's straight section. The beamline was originally aimed at high-throughput data collection for well-diffracting crystals, with off-the-shelf robotics and a stable beam thanks to a simple beamline design. However, it is now fully part of the routine MX user program, for both academic and industrial users alike, since the constraints (5-fold weaker beam than I02/3/4, fixed energy) affect only a subset of MX experiments.

As of April 2015, the beamline is also offering a world-first, namely routine medium-throughtput fragment screening by crystal structure, including all steps from crystal soaking and harvesting to data analysis. D